Childhood maltreatment predicts range of negative outcomes in bipolar patients

first_imgShare on Facebook Share Pinterest Email Share on Twittercenter_img Child maltreatment could predict a range of negative outcomes in patients with bipolar disorder (BD), according to new King’s College London research, which adds to growing evidence on the enduring mental health impact of childhood abuse and neglect.A meta-analysis of 30 studies found that bipolar patients with a history of childhood maltreatment developed BD more than four years earlier than patients with no history of maltreatment. In addition, they were almost twice as likely to attempt suicide and nearly four times more likely to have a diagnosis of post-traumatic stress disorder (PTSD).One in every 25 adults will be diagnosed with bipolar disorder at some point in their life. The disorder is characterised by periods or episodes of feeling very low and lethargic (depression) or of feeling very high and overactive (mania). Bipolar disorder carries the highest risk of suicide among affective disorders: up to 15 per cent of people with bipolar disorder die by suicide. However, not all bipolar patients have these particularly severe outcomes, and there is wide variability in clinical presentation. Therefore, it is important to identify bipolar patients with the greatest clinical need and risk as early as possible, in order to ensure that they receive the most timely and effective interventions to reduce their risk of poor outcomes.Maltreatment in the form of physical, sexual or emotional abuse, or neglect, affects one in five children under 18 in the UK and is known to be highly prevalent in bipolar patients (up to 60 percent). Maltreatment predicts negative outcomes in depressed patients, but it was previously unclear if information on maltreatment could help identify early those bipolar patients with greater clinical needs and risk.The study, published today in The Lancet Psychiatry, found that bipolar patients with a history of childhood maltreatment had more severe manic, depressive and psychotic symptoms; higher risk of post-traumatic stress disorder (PTSD), anxiety disorders, and substance and alcohol misuse disorders; earlier onset of symptoms; more frequent manic and depressive episodes; and higher risk of suicide attempt.Dr Jessica Agnew-Blais, Post-doctoral Researcher from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and lead author of the study, said: ‘These findings lend support to the notion that maltreatment can affect neurobiological processes associated with progression of the disorder.‘Our findings have important implications for clinical practice, as they suggest that a history of childhood maltreatment could be used as an early indicator of high risk for poor outcomes among individuals with bipolar disorder. This information could be valuable for identifying patients with bipolar disorder who may benefit from greater support and treatment.’Dr Andrea Danese, Senior Lecturer from the IoPPN at King’s College London and senior author of the study, said: ‘Future research should identify mechanisms that link childhood maltreatment to unfavourable clinical outcomes in BD, which is associated with disability and life-threatening risks.‘We hope this study will point to vulnerabilities that could inform innovative treatment strategies for people with BD, including anti-inflammatory medications or treatments aimed at trauma and anxiety-related symptoms.’Dr Danese added: ‘Further studies are also needed to assess whether childhood maltreatment predicts treatment response among patients with BD, as has been suggested by early research in this area.’ LinkedInlast_img read more

Lauderhill Police Officer Who Died from COVID-19 Complications Promoted to Rank…

first_imgThe Lauderhill Police Department posthumously promoted Officer Corey Pendergrass, one of their fellow officers who died after a battle with the coronavirus, to the rank of Sergeant. The City of Lauderhill Police Department today released the following statement: First responders, earlier this week, escorted Pendergrass’ body from Plantation General Hospital to a funeral home in Pompano Beach. A private funeral is to take place next weekend to honor the officer. Corey’s life and legacy will be honored by many in the upcoming weeks. However, due to these unprecedented times, The Pendergrass Family has elected to honor Corey with private family services on August 7th and 8th 2020. We suffered a great loss when Corey Pendergrass was taken from us on July 26, 2020. Not only was Corey a great person, a community leader, a friend and officer; he was an incredible Husband and Father. As Police Officers, we understand and have accepted the inherent risk that comes with the profession of our choice. In that same vein, knowing that risk, does not lessen the pain of losing one of our own.center_img On Sunday, the agency announced that Pendergrass had died from complications related to COVID-19. He served on the force since 1997. On July 30, 2020, Police Chief Constance Stanley announced that Corey Pendergrass was posthumously promoted by the City to the rank of Sergeant. We thank him for his 23 years of dedicated service to the law enforcement profession and the entire Lauderhill family. The Lauderhill Police Department will honor Corey’s life and legacy in the near future with a celebration of Life Ceremony. Information for that celebration will be forthcoming. We sincerely thank everyone for all your support and look forward to healing as a City, Department, Community, and Family.last_img read more

Australia swim coach Verhaeren quits after Tokyo delay

first_imgVerhaeren had hoped to make a triumphant departure after leading Australia’s campaign in Japan, but decided against staying Down Under for an extra year to attend the rescheduled Games.“I tried to look for ways to extend, but you can’t compromise in a high performance environment, nor did I want to compromise my family,” the highly respected coach said in a statement released by Swimming Australia.Verhaeren, 51, was appointed in 2013 after Australia’s poor results at the London Olympics a year earlier, a campaign marred by ill-discipline, drug use and drunkenness.At the time, he was best known best known for guiding Dutch greats Pieter van den Hoogenband and Inge de Bruijn to Olympic success in Sydney and Athens.He helped restore Australia as a swimming superpower, with the squad finishing second only to the United States at the 2015 and 2019 world titles.“(He) has overseen significant change and development in a complex system, laying a strong foundation for future success,” Swimming Australia chief executive Leigh Russell said.She said Verhaeren was leaving with Swimming Australia’s best wishes and had decided “it is the right time to put family needs above anything else”.He will be replaced by Australian Rohan Taylor, who is currently state coach for Victoria and Tasmania.The pair will work together during a transition period before Verhaeren departs in September.last_img read more


first_imgNext Game: Nipissing University 1/18/2019 | 8:00 p.m. The University of Toronto Varsity Blues men’s basketball team bounced the Queen’s Gaels 71-67 on Saturday (Jan. 12) night at Kingston, Ont.TORONTO STATS: Fourth-year forward Daniel Johansson recorded his second double-double of the season with a team-high 17 points and 12 rebounds, while fourth-year forward Nikola Paradina chipped in with 17 points.Fourth-year guard Christopher Barret filled up the stat sheet with 11 points, five assists and four rebounds. First-year guard Inaki Alvarez also hit double-digits with 10 points and two assists.HOW IT HAPPENED: The Blues got off to an early 17-8 run, which helped the team take a 20-15 lead after the opening quarter. Toronto continued the momentum ending on a 14-4 run to take a 41-28 advantage into halftime. Daniel Johansson had 13 points and six rebounds in the first half.  U of T was outscored by Queen’s 18-13 in the third, but went into the final quarter up 54-46. The Gaels continued to cut into the Blues lead, but weren’t able to get any closer then four the rest of the way.UP NEXT: Next up for the Blues are the Nipissing Lakers next Friday (Jan. 18) night. Tip off is scheduled for 8:00 p.m., at Goldring Centre for High Performance Sport. For more information, scores and highlights on your favourite U of T athletes and teams, please visit Don’t forget to follow us on Twitter, Instagram, SnapChat and Facebook for the latest and greatest in Varsity Blues intercollegiate athletics.  Print Friendly Version Preview Buy Tickets Live Statscenter_img Matchup History Watch Live Full Schedule Roster last_img read more